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I have major depression. Also I have a spinal fusion.I have tried many depression drugs. I also suffer from a sleep disorder that makes me sleep through a lot of the day. With Pristiq I definitely feel better in the morning and that was the worst time of day for me. I am still suffering from excessive sleepiness during the day. I have been on Pristiq for about three months now. So far its been pretty good. I would recommend it, but it is not a miracle drug for me. I still have depression.I was hoping for a bigger difference.
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I'm a 30 yr old male. I was on Zoloft for 5 years (gained 40lbs, couldn't ejaculate) then Cymbalta (nasty side effects). For a couple months My Psych doctor let me try Pristiq. I loved it. I had/have awful anxiety and panic attacks with depression. (My anxiety is because of my depression). This medicine worked quick and I'm now in my 7th month at 50mg once a day. The last week, it seemed to dwindle down a little (not sure why?), as my depression and anxiety started coming back. My same doctor just upped my dosage to 100mg a day. I'm hoping it wont let me down! I have to say that Pristiq is the best of 3 anti-depressants/anxiety medicines I have tried. Thanks all and good luck.

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