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If you are taking aspirin 81 mg to 325 mg once a day for your heart, this should not interfere with valproate.

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The Food and Drug Administration (FDA) approved Depakote for epilepsy treatment in 1983.

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Additional funding was obtained from GlaxoSmithKline for a study of lamotrigine, during which the antiepileptic-study database was constructed.

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In the 1990s, antipsychotics were "still seen as treatments for the most serious mental illnesses, like hallucinatory schizophrenia, and recast them for much broader uses".

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Valproate products are FDA-approved drugs to treat epileptic seizures, and manic or mixed episodes associated with bipolar disorder (manic-depressive disorder), and to prevent migraine headaches.

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Maternal valproate use during pregnancy for any indication increases the risk of congenital malformations, particularly neural tube defects, but also malformations involving other body systems (e.

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